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Autore principale: | Rheinberger, Hans-Jörg, 1946-
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Titolo: | From microsomes to ribosomes : strategies of representation / Hans-Jörg Rheinberger. |
Abstract: | 'I intend to exemplify these counterintuitive issues on strategy' and representation' in science by going into considerable detail about a research process that originated at the Rockefeller Institute for Medical Research. It started, in 1911, with Peyton Rous's tentative identification of a cancer-inducing agent as an ultramicroscopic organism. Through a series of "unprecedented events" made possible by the conjunction of different techniques of representation, including ultracentrifugation and electron microscopy, this agent was replaced by what for a long time was considered to be, and was structurally described as, a microsome. Through another shift, the microsomal pellet differentiated into a membrane part and a protein-synthesizing organelle, which came to be referred to as the ribosome by the late 1950s.' |
In: | Journal of the history of biology Vol. 28 (1995), p. 49-89 |
Discipline: | Microbiologia e Immunologia--Accademie e istituzioni. |
Enti: | Rockefeller institute for medical research. |
Luoghi: | Stati Uniti. |
Sudd. cronologiche: | Secolo XX. |
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